2-Nitrobenzyl chloride → 2-Benzyl-nitrobenzene

HRID 1282870Notes

Reaction equation

HRID 1282870 reaction equation
[N+:1]([C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6]Cl)([O-:3])=[O:2]>C1C=CC=CC=1>[CH:4]1[CH:11]=[CH:10][C:9]([CH2:6][C:5]2[C:4]([N+:1]([O-:3])=[O:2])=[CH:11][CH:10]=[CH:9][CH:8]=2)=[CH:8][CH:5]=1

Participants

3

Reactant 1

HCID 119212-Nitrobenzyl chloride

Product 1

HCID 3155932-Benzyl-nitrobenzene

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

The reactions of this example use the procedures of Example 1. 2-Nitrobenzyl chloride is reacted with benzene to give 2-nitrodiphenylmethane which is reduced to 2-aminodiphenylmethane. The 2-aminodiphenylmethane is reacted with trifluoromethanesulfonic anhydride to give 2-benzyltrifluoromethanesulfonanilide, m.p. 55°-56.5° C.

Sources & evidence

ORD record
ord-fc2ce43dc9bf49dbb4eb393bfe5725b1
Source dataset
uspto-grants-1976_08
Patent number
US03972926

Reaction notes

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