Hydrazine hydrate (1:1) → HCID 178427940, compound

HRID 1282885Notes

Reaction equation

HRID 1282885 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([NH:8][C:9](=[NH:12])SC)[CH:5]=[C:4]([Cl:13])[C:3]=1[CH3:14].[NH2:15][NH2:16].O>C(O)C>[Cl:1][C:2]1[CH:7]=[C:6]([NH:8][C:9]([NH2:12])=[N:15][NH2:16])[CH:5]=[C:4]([Cl:13])[C:3]=1[CH3:14]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 178504006HCID 178504006, compound

Product 1

HCID 178427940HCID 178427940, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

To 7.18 g of 1-(2,6-dichloro-4-tolyl)-2-methylisothiourea.HJ (C), suspended in 26 ml of ethanol, 1.3 ml of hydrazine.hydrate is added after which the mixture is refluxed for 20 hours. The precipitate formed is filtered off and the filtrate evaporated to dryness. Yield: 6.35 g. Melting point HJ salt: 203°-205°C; melting point HCl salt: 149°-150°C.

Workup

  1. temperatureis refluxed for 20 hours
  2. customThe precipitate formed
  3. filtrationis filtered off
  4. customthe filtrate evaporated to dryness
  5. custom203°-205°C
  6. custom149°-150°C.

Sources & evidence

ORD record
ord-b58bb9c9c9764708a0f64fd6da65ee9c
Source dataset
uspto-grants-1976_08
Patent number
US03972932

Reaction notes

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