Methyl Isocyanate → HCID 131710414, compound

Participants

Reaction Steps

A solution of 8.0 g (0.034 mols) of 3-tert.butyl-4H-1,2,4-triazol-5-yl-N,N-dimethylsulfonamide and 3.4 g (0.06 mol) of methyl isocyanate in 20 ml of triethylamine is stirred overnight at room temperature. The solvent is evaporated under vacuum and the residue is slurried in water. The resultant solid is collected by filtration and recrystallized from ethanol to give 1-N-methylcarbamyl-3-tert.butyl-1,2,4-triazol-5-yl-N,N-dimethylsulfonamide, m.p. 193°-194.5°.

Provenance & Evidence