2-Amino-4-methylthiazole → HCID 86737654, compound

HRID 128292Notes

Reaction equation

HRID 128292 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]2[C:8]3[S:13](=[O:15])(=[O:14])[N:12]([CH3:16])[C:11]([C:17](OC)=[O:18])=[C:10]([OH:21])[C:9]=3[S:22][C:4]=2[CH:3]=1.[NH2:23][C:24]1[S:25][CH:26]=[C:27]([CH3:29])[N:28]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]2[C:8]3[S:13](=[O:14])(=[O:15])[N:12]([CH3:16])[C:11]([C:17]([NH:23][C:24]4[S:25][CH:26]=[C:27]([CH3:29])[N:28]=4)=[O:18])=[C:10]([OH:21])[C:9]=3[S:22][C:4]=2[CH:3]=1

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 70579947HCID 70579947, compound

Product 1

HCID 86737654HCID 86737654, compoundYield 36%

Procedure

Prepared analogous to Example 1 from methyl 7-chloro-4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 2-amino-4-methyl-thiazole with a yield of 36% of theory.

Sources & evidence

ORD record
ord-43ec6c6947e74f02b702695c10f6c980
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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