Sodium Hydroxide → HCID 53735981, compound

Participants

Reaction Steps

36.4 ml of 1 N sodium hydroxide solution are added dropwise to a solution of 10.4 g of α-cyano-α-methyl-2-phenyl-6-quinolineacetic acid methyl ester in 580 ml of ethanol at room temperature. The reaction mixture is stirred for 16 hours at room temperature and evaporated to dryness, the residue is treated with water and the suspension thereby produced is filtered off. After drying in vacuo at 40°C, crude α-methyl-2-phenyl-6-quinolineacetonitrile is obtained, which is directly processed further.

Provenance & Evidence