Benzoyl Peroxide → HCID 21520539, compound

HRID 1282952Notes

Reaction equation

HRID 1282952 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][CH:10]=[C:11]([CH3:16])[CH:12]=2)[N:7]=1.[Br:17]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]1[CH:15]=[CH:14][C:13]2[C:8](=[CH:9][CH:10]=[C:11]([CH2:16][Br:17])[CH:12]=2)[N:7]=1

Participants

5

Reactant 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 2513666-methyl-2-(thiophen-2-yl)quinoline

Product 1

HCID 21520539HCID 21520539, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent

Procedure

11.9 g of 2-(2-thienyl)-6-methyl-quinoline together with 360 ml of carbon tetrachloride, 10.4 g of N-bromosuccinimide and 0.3 g of dibenzoyl peroxide are boiled for 15 hours under reflux. The reaction mixture is cooled and filtered off. Concentration of the filtrate yields 2-(2-thienyl)-6-bromomethyl-quinoline which melts at 95°C.

Workup

  1. temperatureunder reflux
  2. temperatureThe reaction mixture is cooled
  3. filtrationfiltered off

Sources & evidence

ORD record
ord-70699420fc324ddb938ad37248bc0f76
Source dataset
uspto-grants-1976_08
Patent number
US03973022

Reaction notes

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