Ammonia → 2-oxoimidazolidine-1-carboxamide

HRID 1283013Notes

Reaction equation

HRID 1283013 reaction equation
Cl[C:2]([N:4]1[CH2:8][CH2:7][NH:6][C:5]1=[O:9])=[O:3].[NH3:10]>O1CCCC1>[NH2:10][C:2]([N:4]1[CH2:8][CH2:7][NH:6][C:5]1=[O:9])=[O:3]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 832412-Oxoimidazolidine-1-carbonyl chloride

Product 1

HCID 2621102-oxoimidazolidine-1-carboxamide

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

29.7 parts by weight of N-chlorocarbonyl-imidazolid-2-one, were reacted at pH = 8.5 and room temperature with 20 parts by volume of 25% strength aqueous solution of NH3 in 80% strength aqueous tetrahydrofurane. After stripping off the tetrahydrofurane in vacuo, the product which precipitated was filtered off and washed with a little ice water. Yield after drying over P2O5 in a desiccator: 62%. Melting point 200° C.

Workup

  1. customthe product which precipitated
  2. filtrationwas filtered off
  3. washwashed with a little ice water
  4. customYield
  5. dry with materialafter drying over P2O5 in a desiccator

Sources & evidence

ORD record
ord-589474f79d9540f68bbbb6d5dc190186
Source dataset
uspto-grants-1976_08
Patent number
US03974141

Reaction notes

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