Acetyl chloride → HCID 68139952, compound

Participants

Reaction Steps

2-(p-Benzyloxyphenyl)-1-(2-dimethylamino-1-methylethyl)cyclohexanol hydrochloride (11.3 g) is stirred with 140 ml chloroform and 26 g potassium carbonate. Acetyl chloride (6.5 ml) is added and the mixture is stirred overnight, washed with water, and the chloroform dried. The chloroform solution is stirred for 6 hours with 6.5 ml acetyl chloride and 26 g potassium carbonate, then washed with water, dried and concentrated to give 14 g crude product.

Provenance & Evidence