反应详情

A mixture of ethyl p-aminocinnamate, 5.9 g. 4-bromobutylcycloheptane and one equivalent of anhydrous powdered potassium carbonate in 50 ml. hexamethylphosphoramide is heated for 20 hours at 60° C. The mixture is then cooled, diluted with water and extracted with ether. The combined ether extracts are dried, filtered and evaporated. Crystallization from acetonitrile provides the title compound as white crystals.

1. temperatureThe mixture is then cooled
2. extractionextracted with ether
3. dry with materialThe combined ether extracts are dried
4. filtrationfiltered
5. customevaporated
6. customCrystallization from acetonitrile