Acetic Acid → Acetanilide

HRID 1283230Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1283230
[PH4+].[C:2]([OH:5])(=O)[CH3:3].[NH2:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>>[C:2]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1)(=[O:5])[CH3:3]

Komponenten

4

Edukt 3

HCID 176Acetic AcidHCID 6115AnilineHCID 5460504Phosphonium

Produkt 1

HCID 904AcetanilideAusbeute 90 %

Versuchsvorschrift

To the same reaction mixture containing the phosphonium salt as in Example 1 was added a mixture of 3.0 g. (0.05 mole) of acetic acid and 5.2 g. (0.056 mole) of aniline, and the resulting mixture was reacted under reflux for 2 hours. Thereafter, the same aftertreatment as in Example 1 was effected to obtain acetanilide, yield 90% based on acetic acid.

Aufarbeitung

  1. additionwas added
  2. additiona mixture of 3.0 g
  3. temperatureunder reflux for 2 hours

Quellen und Nachweise

ORD-Eintrag
ord-a2160699618b4e5393651293ef47bf0b
Quelldatensatz
uspto-grants-1976_08
Patentnummer
US03974219

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