Sodium Hydroxide → HCID 53696864, compound

HRID 1283277Notes

Reaction equation

HRID 1283277 reaction equation
C[O:2][C:3]([C:5]1[CH:18]=[CH:17][C:8]([CH:9]=[CH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)=[CH:7][CH:6]=1)=[O:4].[OH-].[Na+]>C(O)(=O)C>[C:3]([C:5]1[CH:6]=[CH:7][C:8]([CH:9]=[CH:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=2)=[CH:17][CH:18]=1)([OH:4])=[O:2]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53961811HCID 53961811, compound

Product 1

HCID 53696864HCID 53696864, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2-(4-Methoxycarbonylstyryl) pyridine (2.00g) and 20% w/v aqueous sodium hydroxide (100 ml) were stirred and refluxed for 2 hours. The reaction mixture was cooled, acidified with glacial acetic acid the solid filtered off, dried and recrystallised from ethanol. This gave 1.68 g (90%) 2 Carboxy styryl) pyridine MPT 228°C.

Workup

  1. temperaturerefluxed for 2 hours
  2. temperatureThe reaction mixture was cooled
  3. filtrationfiltered off
  4. customdried
  5. customrecrystallised from ethanol
  6. custompyridine MPT 228°C.

Sources & evidence

ORD record
ord-5663f30993fa45a8b8e15cd24c360db2
Source dataset
uspto-grants-1976_08
Patent number
US03974282

Reaction notes

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