1-Octanol → HCID 21245368, compound

HRID 1283368Notes

Reaction equation

HRID 1283368 reaction equation
[CH2:1]([O:3][C:4]([CH2:6][N:7]1[C:12]([CH3:14])([CH3:13])[CH2:11][CH2:10][CH2:9][C:8]1([CH3:16])[CH3:15])=[O:5])[CH3:2].[CH2:17](O)[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22]CC.[NH2-].[Li+]>C(O)C>[CH2:1]([O:3][C:4]([CH2:6][N:7]1[C:12]([CH3:14])([CH3:13])[CH2:11][CH2:10][CH2:9][C:8]1([CH3:15])[CH3:16])=[O:5])[CH2:2][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH3:22]

Participants

5

Reactant 3

HCID 9571-OctanolHCID 24532Lithium amideHCID 20238190HCID 20238190, compound

Product 1

HCID 21245368HCID 21245368, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 45.4 parts of 1-ethoxycarbonylmethyl-2,2,6,6-tetramethylpiperidine, 36.5 parts of 1-octanol and 0.5 part of lithium amide was heated at 110°-115°C for 48 hours, the ethyl alcohol formed during the reaction being removed by distillation. Fractional distillation of the reaction mixture gave 1-octoxycarbonylmethyl-2,2,6,6-tetramethylpiperidine having a boiling point of 120°C/0.005 mm Hg.

Workup

  1. temperaturewas heated at 110°-115°C for 48 hours
  2. custombeing removed by distillation
  3. distillationFractional distillation of the reaction mixture

Sources & evidence

ORD record
ord-f68c3c4837f84f6da5dc0e3ceade9d7e
Source dataset
uspto-grants-1976_08
Patent number
US03975357

Reaction notes

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