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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1283403Generated: October 30, 2026

Hydrazine hydrate (1:1) → 6-(3-Chloro-4-methoxyphenyl)-4,5-dihydro-3(2H)-pyridazinone

https://huagongshe.com/reaction/1283403

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazine hydrate (1:1)HCID 24654—
ReactantBenzenebutanoic acid, 3-chloro-4-methoxy-gamma-oxo-HCID 10060312—
Product6-(3-Chloro-4-methoxyphenyl)-4,5-dihydro-3(2H)-pyridazinoneHCID 1082387684%

Reaction Steps

This compound was prepared in 84% yield by reaction of 3-(3-chloro-4-methoxybenzoyl)propionic acid with hydrazine hydrate in ethanolic solution at reflux temperature for 5 hours. It had mp 194°-195°C after crystallisation from ethanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03975388
Source datasetuspto-grants-1976_08
ORD IDord-0b1d343a9ce642808535b831c78997e0
Source noteuspto-grants-1976_08