反应详情

To a solution of 10.12 g (0.10 mol) of triethylamie, 18.72 g (0.10 mol) of N-(2-hydroxyphenyl)methanesulfonamide and 300 ml of methylene chloride cooled to 0° C. was added a solution of 10.45 g (0.10 mol) of methacryloyl chloride in 100 ml of methylene chloride over a 15-minute period. After stirring 2 hours at reduced temperature, the solution was washed three times with water, dried over magnesium sulfate and concentrated to an oil. On cooling and scratching, the oil crystallized. Recrystallization from 1:1 benzene:hexane gave a white solid which was collected, washed with 1:1 benzene:hexane, and dried at room temperature in vacuo. The yield of N-(2-methacryloyloxyphenyl)methanesulfonamide was 10.4 g (40.7 percent); m.p.=88° to 90° C.

1. washthe solution was washed three times with water
2. dry with materialdried over magnesium sulfate
3. concentrationconcentrated to an oil
4. temperatureOn cooling
5. customthe oil crystallized
6. customRecrystallization from 1:1 benzene
7. customhexane gave a white solid which
8. customwas collected
9. washwashed with 1:1 benzene
10. dry with materialhexane, and dried at room temperature in vacuo