HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21518480, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | HCID 21518492 | HCID 21518492 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 21518480 | HCID 21518480 | 97% |
Reaction Steps
1-Thiomorpholino-3-piperazino-5-chloro-isoquinoline was prepared analogous to Example 3 from 1-thiomorpholino-3,5-dichloro-isoquinoline and piperazine by heating in diphenyl ether at 200°C. M.p. of its hydrochloride: 273°-275°C (from water); yield: 97% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975524 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-324dba09a8c44665ac99663d1f6eda93 |
| Source note | uspto-grants-1976_08 |