HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 21518477, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | Maleate(2-) | HCID 5288227 | — |
| Reactant | HCID 21518474 | HCID 21518474 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 21518477 | HCID 21518477 | 85% |
Reaction Steps
1-Thiomorpholino-3-piperazino-7-chloro-isoquinoline was prepared analogous to Example 3 from 1-thiomorpholino-3,7-dichloro-isoquinoline and piperazine by heating in diphenyl ether at 200°C. M.p. of its maleate: 188°-190°C (from ethanol); yield: 85% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975524 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-a672168e2c1a4cccbf0c07aad2db73aa |
| Source note | uspto-grants-1976_08 |