HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → HCID 21518487, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | HCID 21518469 | HCID 21518469 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | HCID 21518487 | HCID 21518487 | 90% |
Reaction Steps
1-Thiomorpholino-3-piperazino-5-fluoro-isoquinoline was prepared analogous to Example 3 from 1-thiomorpholino-3-chloro-5-fluoro-isoquinoline by heating for 30 hours with piperazine in diphenyl ether at 200°C. M.p. 213°-215°C (from isopropanol); yield: 90% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975524 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-37fb5301cec14192afced9cc79d80c91 |
| Source note | uspto-grants-1976_08 |