HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 21518466, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | HCID 21518467 | HCID 21518467 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21518466 | HCID 21518466 | 53% |
Reaction Steps
1-Thiomorpholino-3-piperazino-5-nitro-isoquinoline was prepared analogous to Example 3 from 1-thiomorpholino-3-chloro-5-nitro-isoquinoline by heating for 5 hours with piperazine in dioxane at 100°C. M.p. of its hydrochloride: 245°-247°C (from water); yield: 53% of theory.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975524 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-32c80f7c88884849b2806f5a045162f3 |
| Source note | uspto-grants-1976_08 |