Hydrogen Peroxide → HCID 53846113, compound

HRID 1283591Notes

Reaction equation

HRID 1283591 reaction equation
[S:1]1[CH2:6][CH2:5][N:4]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([Cl:17])[CH:15]=3)[CH:10]=[C:9]([N:18]3[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]3)[N:8]=2)[CH2:3][CH2:2]1.[OH:24]O>C(O)(=O)C>[O:24]=[S:1]1[CH2:6][CH2:5][N:4]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[C:14]([Cl:17])[CH:15]=3)[CH:10]=[C:9]([N:18]3[CH2:23][CH2:22][NH:21][CH2:20][CH2:19]3)[N:8]=2)[CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 21518477HCID 21518477, compound

Product 1

HCID 53846113HCID 53846113, compoundYield 13%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1-(1-Oxido-thiomorpholino)-3-piperazino-7-chloro-isoquinoline was prepared analogous to Example 12 from 1-thiomorpholino-3-piperazino-7-chloro-isoquinoline by oxidation with hydrogen peroxide in glacial acetic acid. M.p. 209°-211°C; yield: 13% of theory.

Sources & evidence

ORD record
ord-884fed4b3e964f598b4a06333e718e08
Source dataset
uspto-grants-1976_08
Patent number
US03975524

Reaction notes

Loading…