2-Butylbenzofuran → 2-n-Butyl-3-(2'-methoxybenzoyl)benzofuran

HRID 1283644Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1283644
[CH2:1]([C:5]1[O:6][C:7]2[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=2[CH:9]=1)[CH2:2][CH2:3][CH3:4].[C:14](Cl)(=[O:23])[C:15]1[C:16]([O:21][CH3:22])=[CH:17][CH:18]=[CH:19][CH:20]=1>>[CH2:1]([C:5]1[O:6][C:7]2[CH:13]=[CH:12][CH:11]=[CH:10][C:8]=2[C:9]=1[C:14](=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][C:16]=1[O:21][CH3:22])[CH2:2][CH2:3][CH3:4]

Komponenten

3

Edukt 2

HCID 779512-ButylbenzofuranHCID 889692-Methoxybenzoyl chloride

Produkt 1

HCID 215185952-n-Butyl-3-(2'-methoxybenzoyl)benzofuran

Versuchsvorschrift

Acylation of 9.4 g. (0.054 mol.) of 2-n-butylbenzofuran with 9.9 g. (0.058 mol.) of o-anisoyl chloride according to the procedure described in Example 10 gave 2-n-butyl-3-(2'-methoxybenzoyl)benzofuran which was demethylated with pyridine hydrochloride as previously described to give 2-n-butyl-3-(2'-hydroxybenzoyl)benzofuran.

Quellen und Nachweise

ORD-Eintrag
ord-8015124e0b4a4cfd9a369adf01403c48
Quelldatensatz
uspto-grants-1976_08
Patentnummer
US03975537

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