HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 21518627, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-Butylbenzofuran | HCID 77951 | — |
| Reactant | 4-Chloro-o-anisic acid | HCID 93682 | — |
| Reactant | 4-Chloro-2-methoxybenzoyl chloride | HCID 22142450 | — |
| Product | HCID 21518627 | HCID 21518627 | — |
Reaction Steps
Acylation of 13.1 g. (0.075 mol.) of 2-n-butylbenzofuran with 15.4 g. (0.075 mol.) of 4-chloro-2-methoxybenzoic acid chloride, prepared from 4-chloro-2-methoxybenzoic acid and thionyl chloride as previously described, according to the procedure of Example 10 gave 2-n-butyl-3-(4'-chloro-2'-methoxybenzoyl)benzofuran. Demethylation as previously described gave 2-n-butyl-3-(4'-chloro-2'-hydroxybenzoyl)benzofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975537 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-1dda223998cf41d7841da210c39deb3e |
| Source note | uspto-grants-1976_08 |