HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 5-fluoro-1H-indazol-3-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Amino-5-fluorobenzonitrile | HCID 2737704 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Product | 5-fluoro-1H-indazol-3-amine | HCID 4327896 | — |
Reaction Steps
By the procedure of Example 2, 13.6 g. of 2-cyano-4-fluoroaniline is treated with 8.0 g. of sodium nitrite and concentrated hydrochloric acid, followed by stannous chloride to give 3-amino-5-fluoroindazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | USRE028939 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-ed1e662a57e14dce96aaf57815ac46d4 |
| Source note | uspto-grants-1976_08 |