反应详情

To a suspension of N-methoxycarbonyl-L-phenylalanine (1.65 g) and triethylamine (2.8 ml) in dry chloroform (15 ml), ethyl 2-methoxycarbonyloxyimino-2-cyanoacetate (4.0 g) is added, and the resulting mixture is stirred at room temperature for 2 hours. The reaction mixture is treated as in Example B to give N-methoxycarbonyl-L-phenylalanine methyl ester (1.2 g) as an oil.

1. additionis added
2. additionThe reaction mixture is treated as in Example B