Dimethylformamide → HCID 21516502, compound

HRID 1283783Notes

Reaction equation

HRID 1283783 reaction equation
[N+:1]([C:4]1[C:9]([CH3:10])=[CH:8][CH:7]=[CH:6][C:5]=1[CH3:11])([O-:3])=[O:2].[CH3:12][N:13]([CH3:16])[CH:14]=O>C(O)C>[CH3:12][N:13]([CH3:16])/[CH:14]=[CH:11]/[C:5]1[CH:6]=[CH:7][CH:8]=[C:9]([CH3:10])[C:4]=1[N+:1]([O-:3])=[O:2]

Participants

4

Reactant 2

HCID 6228DimethylformamideHCID 66722,6-Dimethylnitrobenzene

Product 1

HCID 21516502HCID 21516502, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A 500 -ml. three-necked flask fitted with a thermometer, a 15-cm. Vigreux column connected to a descending condenser and receiver with a nitrogen inlet was charged with 30.23 g. of 2-nitro-m-xylene, 64.77 g. of N,N-domethylformamide diethyl acetal, and 200 ml. of N,N-dimethylformamide. The reaction vessel was then immersed in an oil bath, preheated to 165°, for 46 hours. The pot temperature was maintained above 140° by continuous distillation of the formed ethanol.

Workup

  1. customthree-necked flask fitted with a thermometer
  2. customVigreux column connected to a descending condenser
  3. additionreceiver with a nitrogen inlet was charged with 30.23 g
  4. customThe reaction vessel was then immersed in an oil bath

Sources & evidence

ORD record
ord-f5fd04378ad649b19296e1e6f2a953e1
Source dataset
uspto-grants-1976_08
Patent number
US03976639

Reaction notes

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