反应详情

2-Pyrrolidineheptanoic acid is prepared from N-t-butoxycarbonylproline following steps A and B of Example 4 and step C of the procedure of Example 15. In step C, benzyl ω -chlorohexanoate is substituted for the 1-chloroheptane. The product thus obtained is hydrogenated in the presence of 10% palladium on charcoal and is then treated with trifluoroacetic acid, as in step E of the same procedure.

1. customThe product thus obtained