Hydrochloric Acid → HCID 86733512, compound

HRID 1283879Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][NH:11][C:12]([CH:15]([OH:28])[C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[C:18]([CH2:23][S:24]([CH3:27])(=[O:26])=[O:25])[CH:17]=2)([CH3:14])[CH3:13])=[CH:5][CH:4]=1.[ClH:29]>>[ClH:29].[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH2:10][NH:11][C:12]([CH:15]([OH:28])[C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[C:18]([CH2:23][S:24]([CH3:27])(=[O:25])=[O:26])[CH:17]=2)([CH3:14])[CH3:13])=[CH:7][CH:8]=1

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 86733513HCID 86733513, compound

Product 1

HCID 86733512HCID 86733512, compound

Procedure

The alcohol is treated with hydrogen chloride in methanol-ether giving α-[2-(4-methoxyphenyl)-1,1-dimethylethylaminomethyl]-4-hydroxy-3-(methylsulfonylmethyl)benzyl alcohol hydrochloride as colorless crystals having a melting point of 180°-182°C.

Sources & evidence

ORD record: ord-ceeb2ae915834c22abc586c82a9d552a
Source dataset: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03976694

Reaction notes

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