Propylamine → HCID 13337019, compound

HRID 128395Notes

Reaction equation

HRID 128395 reaction equation
[C:1]([C:3]1[C:8]([C:9]#[N:10])=[N:7][C:6](Cl)=[C:5]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)[N:4]=1)#[N:2].[CH2:19]([NH2:22])[CH2:20][CH3:21]>>[C:1]([C:3]1[C:8]([C:9]#[N:10])=[N:7][C:6]([NH:22][CH2:19][CH2:20][CH3:21])=[C:5]([C:12]2[CH:17]=[CH:16][C:15]([CH3:18])=[CH:14][CH:13]=2)[N:4]=1)#[N:2]

Participants

3

Reactant 2

HCID 7852PropylamineHCID 12907212HCID 12907212, compound

Product 1

HCID 13337019HCID 13337019, compoundYield 74%

Procedure

2,3-Dicyano-5-chloro-6-p-tolylpyrazine (1.00 g; 0.0039 mole) and 0.46 g (0.0078 mole) of n-propylamine were worked up in the same way as in Example 13, and then recrystallized from toluene to afford 0.80 g (yield 74%) of 2,3-dicyano-5-n-propylamino-6-p-tolylpyrazine.

Workup

  1. customrecrystallized from toluene

Sources & evidence

ORD record
ord-a2fedc458cd94d2db840335c20e44829
Source dataset
uspto-grants-1981_03
Patent number
US04259489

Reaction notes

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