HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dioxane → HCID 12883870, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 682234 | HCID 682234 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | HCID 178418361 | HCID 178418361 | — |
| Product | HCID 12883870 | HCID 12883870 | — |
| Product | HCID 23469705 | HCID 23469705 | — |
Reaction Steps
1-(2-Chlorobenzyl)-2-glycolyl-hydrazine is prepared by reducing 2-chlorobenzaldehyde glycolylhydrazone (41.5 g), dissolved in dioxane (415 cc), with hydrogen in the presence of palladium on charcoal in an autoclave, under hydrogen at a pressure of 15 kg/cm2, at a temperature of between 20° and 60° C. After filtration and concentration, 2-hydroxymethyl-4-(2-chlorobenzyl)-1,3,4-oxadiazolin-5-one (38 g) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04259497 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-cdd8ad48579c44c0ae4f6ffa69098b73 |
| Source note | uspto-grants-1981_03 |