Hydrochloric Acid → HCID 135755441, compound

Participants

Reaction Steps

A mixture of 1-(1-methyl-1H-tetrazol-5-yl)thiomethyl- 6,7-dibenzyloxy-3,4-dihydroisoquinoline (1g), 99% ethanol (10 ml) and concentrated hydrochloric acid (10 ml) was refluxed for 3 hours. After the reaction the solvent was distilled off and the residue was crystallized from a mixture of isopropanol and ether to give 1-(1-methyl-1H-tetrazol-5-yl)thiomethyl- 6,7-dihydroxy-3,4-dihydroisoquinoline hydrochloride (0.75 g), mp 130°C (dec.).

Provenance & Evidence