Butyl isocyanate → HCID 13423322, compound

HRID 1284470Notes

Reaction equation

HRID 1284470 reaction equation
[C:1]1(/[C:7](/[C:15]2[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=2)=[CH:8]\[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][OH:14])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:21]([N:25]=[C:26]=[O:27])[CH2:22][CH2:23][CH3:24]>C(N(CC)CC)C>[CH2:21]([NH:25][C:26]([O:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]/[CH:8]=[C:7](\[C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)/[C:15]1[CH:16]=[N:17][CH:18]=[CH:19][CH:20]=1)=[O:27])[CH2:22][CH2:23][CH3:24]

Participants

4

Reactant 2

HCID 8110Butyl isocyanateHCID 13417327HCID 13417327, compound

Product 1

HCID 13423322HCID 13423322, compoundYield 84.8%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

In the presence of triethylamine, (E)-7-phenyl-7-(3-pyridyl)-6-hepten-1-ol (2.0 g, 7.4 mmoles) was reacted with n-butyl isocyanate (0.8 g) in the same manner as Example 9 to give 1-(n-butyl)aminocarbonyloxy-(E)-7-phenyl-7-(3-pyridyl)-6-heptene (Compound Id-25, 2.3 g) as an oil

Sources & evidence

ORD record
ord-9e2307a51f24439896be1a2c06c44beb
Source dataset
uspto-grants-1986_01
Patent number
US04563446

Reaction notes

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