Chloride → Ethyl 2-(2-chloroethoxyimino)-3-oxo-4-chlorobutyrate

HRID 1284712Notes

Reaction equation

HRID 1284712 reaction equation
[Cl:1][CH2:2][CH2:3][O:4][N:5]=[C:6]([C:12](=[O:14])[CH3:13])[C:7]([O:9][CH2:10][CH3:11])=[O:8].[Cl-:15]>C(O)(=O)C>[Cl:1][CH2:2][CH2:3][O:4][N:5]=[C:6]([C:12](=[O:14])[CH2:13][Cl:15])[C:7]([O:9][CH2:10][CH3:11])=[O:8]

Participants

4

Reactant 2

HCID 312ChlorideHCID 54193086Ethyl 2-[(2-chloroethoxy)imino]-3-oxobutanoate

Product 1

HCID 54169228Ethyl 2-(2-chloroethoxyimino)-3-oxo-4-chlorobutyrateYield 70.4%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Ethyl 2-(2-chloroethoxyimino)-3-oxobutyrate (syn isomer, 83.6 g.), sulfury chloride (52.4 g.) and acetic acid (83.6 ml.) were treated in a similar manner to that of Example F-(2) to give Ethyl 2-(2-chloroethoxyimino)-3-oxo-4-chlorobutyrate (syn isomer, 68 g.), oil.

Sources & evidence

ORD record
ord-0977d1cd20694871a1ab2a2e7ce811b7
Source dataset
uspto-grants-1986_01
Patent number
US04563522

Reaction notes

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