Potassium Carbonate → 2-[4-(2-Thienyl-methoxyiminomethyl)-phenoxy]-2-methyl-propionic acid

Participants

Reaction Conditions

Reaction Steps

2.4 g of ethyl ester obtained in Example 23 and 1.05 g potassium carbonate dissolved in 75% aqueous ethanol (25 ml) are maintained at 80° C. for 5 hours. The alcohol is then evaporated off, the resulting material is made acidic and the acid precipitate is filtered off, to give a mixture of equivalent amounts of both stereoisomers which melts at 168° C.

Provenance & Evidence