反应详情

240 g (2 moles) of acetophenone were dissolved in 300 ml of chloroform and, after addition of 3 ml of ethanol and 109 g (0.64 mole) of fluorodichloromethanesulphenyl chloride, the mixture was heated to the reflux temperature. A further 400 g (2.36 moles) of fluorodichloromethane-sulphenyl chloride were added dropwise in the course of 30 minutes and the mixture was then heated under reflux for 5 hours. For subsequent working up, the reaction mixture was subjected to fractional distillation under reduced pressure. After first runnings of unchanged starting material, 126 g of fluorodichloromethyl-mercaptomethyl phenyl ketone were obtained in the form of a liquid of boiling point 128° C./0.4 mbar.

1. temperaturethe mixture was heated to the reflux temperature
2. temperaturethe mixture was then heated
3. temperatureunder reflux for 5 hours
4. distillationthe reaction mixture was subjected to fractional distillation under reduced pressure