HCID 20251303, compound → HCID 178448899, compound

HRID 1284977Notes

Reaction equation

HRID 1284977 reaction equation
[C:1]([NH:6][C:7]1[CH2:11][CH2:10][N:9]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:21])([F:20])[F:19])[CH:13]=2)[N:8]=1)(=O)[CH2:2][CH2:3][CH3:4].[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[CH2:1]([NH:6][C:7]1[CH2:11][CH2:10][N:9]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([C:18]([F:20])([F:21])[F:19])[CH:13]=2)[N:8]=1)[CH2:2][CH2:3][CH3:4]

Participants

3

Reactant 2

HCID 20251303HCID 20251303, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 178448899HCID 178448899, compound

Procedure

According to the method of Example 1, 3-butyramido-1-(3-trifluoromethylphenyl)-2-pyrazoline was reduced with lithium aluminium hydride to produce 3-butylamino-1-(3-trifluoromethylphenyl)-2-pyrazoline which was a gum (yield 2.4 g) and was recrystallized as the hydrochloride m.p. 173.4° (yield 1.65 g).

Sources & evidence

ORD record
ord-9ba3e0ccd45a4fe98ca21290e0eff78f
Source dataset
uspto-grants-1986_01
Patent number
US04564684

Reaction notes

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