4-Hydroxybenzyl Alcohol → Bromocresol

HRID 1285031Notes

Reaction equation

HRID 1285031 reaction equation
[Br:1]Br.[CH:3]1[C:8]([CH2:9]O)=[CH:7][CH:6]=[C:5]([OH:11])[CH:4]=1>C1C=CC=CC=1>[OH:11][C:5]1[CH:6]=[CH:7][C:8]([CH2:9][Br:1])=[CH:3][CH:4]=1

Participants

4

Reactant 2

HCID 1254-Hydroxybenzyl AlcoholHCID 24408Bromine

Product 1

HCID 41663Bromocresol

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Dried bromine gas (Br2) was blown through a mixed solution of 33 g of p-hydroxybenzyl alcohol ##STR133## and 900 ml of benzene for 2 hours while cooling the solution with ice water. Thereafter, the solution was stirred for 2 hours, and then distilled to obtain p-hydroxybenzyl bromide ##STR134## The boiling point of this compound was 125°-126° C./15 mmHg.

Workup

  1. distillationdistilled

Sources & evidence

ORD record
ord-6704481c08674c2e803fa9170fb077b1
Source dataset
uspto-grants-1986_01
Patent number
US04564694

Reaction notes

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