p-Toluenesulfonic acid → HCID 20249887, compound

HRID 1285131Notes

Reaction equation

HRID 1285131 reaction equation
[CH3:1][N:2]1[C:7]([CH3:8])=[C:6]([C:9]2[CH:14]=[CH:13][N:12]=[CH:11][CH:10]=2)[S:5][CH2:4][C:3]1=[O:15].[C:16]1([CH3:26])[CH:21]=[CH:20][C:19]([S:22]([OH:25])(=[O:24])=[O:23])=[CH:18][CH:17]=1>CO>[C:16]1([CH3:26])[CH:17]=[CH:18][C:19]([S:22]([OH:25])(=[O:23])=[O:24])=[CH:20][CH:21]=1.[CH3:1][N:2]1[C:7]([CH3:8])=[C:6]([C:9]2[CH:10]=[CH:11][N:12]=[CH:13][CH:14]=2)[S:5][CH2:4][C:3]1=[O:15]

Participants

4

Reactant 2

HCID 6101p-Toluenesulfonic acidHCID 13805987HCID 13805987, compound

Product 1

HCID 20249887HCID 20249887, compoundYield 56.3%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 4,5-dimethyl-6-(4-pyridinyl)-2H-1,4-thiazin-3-one (30 mg) in methanol (2 ml), p-toluenesulfonic acid (31.1 mg) was added and the mixture was treated in the same manner as described in Example 1-(3) to give 4,5-dimethyl-6-(4-pyridinyl)-2H-1,4-thiazin-3-one p-toluenesulfonate (30 mg, yield 56.3%).

Workup

  1. additionthe mixture was treated in the same manner

Sources & evidence

ORD record
ord-5c264f7a0d2c47fd938b82e524933aed
Source dataset
uspto-grants-1986_01
Patent number
US04565813

Reaction notes

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