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HRID1285174

反应详情

EQUATION

反应方程式

HRID 1285174 的结构方程式

REACTANTS

反应物

2
结构：Cn1c(=O)c2[nH]cnc2n(C)c1=O
HCID2153

Theophylline

C7H8N4O2

结构：Cc1nc(CC2CO2)no1
HCID20249971

5-Methyl-3-[(oxiran-2-yl)methyl]-1,2,4-oxadiazole

C6H8N2O2

PRODUCTS

生成物

1
结构：Cc1nc(CC(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)no1
HCID20249967

未命名化合物

收率 86%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

结构：CC(C)O
溶剂HCID3776

Isopropanol

C3H8O

PROCEDURE

实验过程

1.4 g. 3-(2,3-epoxy-propyl)-5-methyl-1,2,4-oxadiazole and 1.8 g. of theophylline are boiled under stirring in a mixture of 20 cm3 isopropyl alcohol and 0.1 cm3 of pyridine for 8 hours. 2.75 g. (86% yield) of 7-[2-hydroxy-3-(5-methyl-1,2,4-oxadiazol-3-yl)-propan-1-yl]-theophylline are obtained.