Triethylamine → HCID 178516783, compound

HRID 1285329Notes

Reaction equation

HRID 1285329 reaction equation
[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH2:15])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.I.CS[C:22]1[NH:23][CH2:24][C:25](=[O:27])[N:26]=1.C(N(CC)CC)C>C(O)C>[N:1]1([CH2:7][C:8]2[CH:9]=[C:10]([CH:16]=[CH:17][CH:18]=2)[O:11][CH2:12][CH2:13][CH2:14][NH:15][C:22]2[NH:23][CH2:24][C:25](=[O:27])[N:26]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 102205613-(3-(Piperidin-1-ylmethyl)phenoxy)propan-1-amineHCID 178503565HCID 178503565, compound

Product 1

HCID 178516783HCID 178516783, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

3-(3-Piperidinomethylphenoxy)propylamine (3.01 g), 2-methylthio-imidazolin-4-one hydroiodide (2.60 g) and triethylamine (2.18 g) were refluxed in ethanol (20 ml) for 3 hours.

Sources & evidence

ORD record
ord-5c65a2294af647c08f8fa6c9490d6274
Source dataset
uspto-grants-1986_01
Patent number
US04567176

Reaction notes

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