Acetic-formic anhydride → HCID 178521945, compound

HRID 1285383Notes

Reaction equation

HRID 1285383 reaction equation
[NH2:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([NH:6][C:7]1[NH:11][N:10]=[N:9][N:8]=1)=[O:5].[C:16](OC=O)(=[O:18])C>CN(C)C=O>[CH:16]([NH:1][C:2]1[CH:15]=[CH:14][CH:13]=[CH:12][C:3]=1[C:4]([NH:6][C:7]1[NH:11][N:10]=[N:9][N:8]=1)=[O:5])=[O:18]

Participants

4

Reactant 2

HCID 75269Acetic-formic anhydrideHCID 178507500HCID 178507500, compound

Product 1

HCID 178521945HCID 178521945, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of 4.7 g of 2-amino-N-(1H-tetrazol-5-yl)benzamide in 30 ml of dimethylformamide, under nitrogen, was added 4.7 g of freshly prepared formic acetic anhydride. The precipitate which formed within a few minutes was separated by filtration and washed with ether to give 2-(formylamino)-N-(1H-tetrazol-5-yl)benzamide melting at about 247°-248° C. This compound has the following structural formula: ##STR2##

Workup

  1. customThe precipitate which formed within a few minutes
  2. customwas separated by filtration
  3. washwashed with ether

Sources & evidence

ORD record
ord-6fe94387a4e945ca813b65d259dc1136
Source dataset
uspto-grants-1986_01
Patent number
US04567193

Reaction notes

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