HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 70045178, compound → Ranolazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 70045178 | HCID 70045178 | — |
| Solvent | Sulfuric Acid | HCID 1118 | — |
| Product | Ranolazine | HCID 56959 | — |
Reaction Steps
1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethyl]piperazine acetate (1.0 g) is dissolved in 50 ml 50% aqueous sulfuric acid, and the solution evaporated to dryness. The product is suspended in ethanol and filtered, air dried and recrystallized from methanol/acetone to yield 1-[3-(2-methoxyphenoxy)-2-hydroxypropyl]-4-[(2,6-dimethylphenyl)aminocarbonylmethyl]piperazine.2HSO4.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04567264 |
| Source dataset | uspto-grants-1986_01 |
| ORD ID | ord-ce7bed6fb8e44959a6805bcaab383297 |
| Source note | uspto-grants-1986_01 |