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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 128610Generated: October 31, 2026

Sodium Hydroxide → HCID 178432386, compound

https://huagongshe.com/reaction/128610

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 178469685HCID 178469685—
SolventWaterHCID 962—
ProductHCID 178432386HCID 178432386—

Reaction Conditions

Temperature180 °C

Reaction Steps

A mixture of ethyl 6-bromo-4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate (6.7 g), sodium hydroxide pellets (1.7 g) and water (50 ml) was heated at 180° C. in a pressure vessel for 18 hours. The mixture was cooled and filtered to give 6-bromo-7-methyl-1,8-naphthyridin-4-ol, m.p. >250° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05464781
Source datasetuspto-grants-1995_11
ORD IDord-e005898a381f45a6ab0a0c6b25021445
Source noteuspto-grants-1995_11