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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 128622Generated: October 25, 2026

1-Chloro-4-nitrobenzene → 2-(4-Aminophenoxy)ethanol

https://huagongshe.com/reaction/128622

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-nitrobenzeneHCID 7474—
ReactantSodium CarbonateHCID 10340—
Reactant2-(4-Nitrophenoxy)ethanolHCID 85381—
SolventEthylene GlycolHCID 174—
Product2-(4-Aminophenoxy)ethanolHCID 80892—

Reaction Steps

2-(4-Aminophenoxy)ethanol was prepared, using the method described in Example C3, by the reduction of 2-(4-nitrophenoxy)ethanol which was prepared by heating a mixture of 4-chloronitrobenzene, ethylene glycol and sodium carbonate in a sealed vessel (Beil. 6, II, 222).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05464781
Source datasetuspto-grants-1995_11
ORD IDord-15c442ca4f6c4400b134ad4f89e482c3
Source noteuspto-grants-1995_11