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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 128698Generated: October 30, 2026

N-(alpha-cyclopropylbenzyl)-N-propylthiourea → 4-(2-chloro-4-iodophenyl)-5-methyl-2-[N-(alpha-cyclopropylbenzyl)-N-propylamino]thiazole

https://huagongshe.com/reaction/128698

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(alpha-cyclopropylbenzyl)-N-propylthioureaHCID 18967810—
Reactant2-Bromo-1-(2-chloro-4-iodophenyl)-1-propanoneHCID 18967847—
Product4-(2-chloro-4-iodophenyl)-5-methyl-2-[N-(alpha-cyclopropylbenzyl)-N-propylamino]thiazoleHCID 19374911—

Reaction Steps

This compound was prepared from N-(α-cyclopropylbenzyl)-N-propylthiourea (Compound 75) and 2-bromo-1-(2-chloro-4-iodophenyl)-1-propanone (Compound 18) according to the process described in Example 1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05464847
Source datasetuspto-grants-1995_11
ORD IDord-e57271fb0a4b410c80ca9fde671e8b0e
Source noteuspto-grants-1995_11