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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1287021Generated: October 30, 2026

3-Bromopyridine → Biphenyl

https://huagongshe.com/reaction/1287021

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-BromopyridineHCID 12286—
ReactantEthyl CinnamateHCID 637758—
Reagent2,N'3,N'3,N3,N3,N'5,N'5,N5,N5-nonamethyl-2,4,6-triaza-3lambda5,5lambda5-diphosphaocta-3,5-diene-3,3,5,5-tetramineHCID 3393106—
ReagentHCID 178439017HCID 178439017—
SolventDimethyl SulfoxideHCID 679—
ProductBiphenylHCID 7095—
Product3-BromopyridineHCID 12286—
ProductEthyl CinnamateHCID 637758—
ProductHCID 178470870HCID 178470870—

Reaction Steps

The Mosquito was used to combine the source plate solutions by multi-aspiration of 250 nL of each of the four reaction components and then to dose the resulting reaction mixture (1 uL) into a 1536-well plate

Provenance & Evidence

DOI10.1126/science.1259203
Source datasetHTE Pd-catalyzed cross-coupling screen
ORD IDord-c2b2d4f1b2fc4cdb8272d5bedbda11d5
Source noteHTE Pd-catalyzed cross-coupling screen