反应详情

4-Biphenylsulfonic acid (3.0 g, 12.8 mmol) was heated at 70° C. with phosphorus oxychloride (1.30 ml, 14.0 mol) for 2 h. Excess phosphorus oxychloride was removed under reduced pressure. The residue was decomposed with ice water and extracted with ethyl acetate. The extract was washed with 5% sodium bicarbonate solution, dried over anhydrous magnesium sulfate and concentrated to yield 2.9 crude 4-biphenylsulfonyl chloride.

1. customExcess phosphorus oxychloride was removed under reduced pressure
2. extractionextracted with ethyl acetate
3. washThe extract was washed with 5% sodium bicarbonate solution
4. dry with materialdried over anhydrous magnesium sulfate
5. concentrationconcentrated