Methyl Bromide → HCID 21507480, compound

HRID 1287231Notes

Reaction equation

HRID 1287231 reaction equation
Cl.[C:2]([CH:10]1[C:15](=[O:16])[N:14]([CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])[C:13]2[CH:22]=[CH:23][CH:24]=[CH:25][C:12]=2[S:11]1)(=[O:9])[C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.CBr>C(#N)C>[C:2]([CH:10]1[C:15](=[O:16])[N:14]([CH2:17][CH2:18][N:19]([CH3:21])[CH3:20])[C:13]2[CH:22]=[CH:23][CH:24]=[CH:25][C:12]=2[S:11]1)(=[O:9])[C:3]1[CH:4]=[CH:5][CH:6]=[CH:7][CH:8]=1

Participants

4

Reactant 2

HCID 6323Methyl BromideHCID 131710468HCID 131710468, compound

Product 1

HCID 21507480HCID 21507480, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

A solution of the free base of Example 1 in acetonitrile is treated with two equivalents of methyl bromide and the solution allowed to stand at room temperature for 8 hours. The solvent is removed to give the product.

Workup

  1. customThe solvent is removed
  2. customto give the product

Sources & evidence

ORD record
ord-4fb04f5a808841b29efcdcc21cef6fb8
Source dataset
uspto-grants-1976_10
Patent number
US03984405

Reaction notes

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