Benzene → HCID 20322125, compound

HRID 1287348Notes

Reaction equation

HRID 1287348 reaction equation
C([O:3][C:4](=[O:18])[CH:5]([CH2:11][CH2:12][CH:13]([CH3:17])[CH2:14][CH2:15][Br:16])C(OCC)=O)C.Br.C1C=CC=CC=1>O>[Br:16][CH2:15][CH2:14][CH:13]([CH3:17])[CH2:12][CH2:11][CH2:5][C:4]([OH:18])=[O:3]

Participants

5

Reactant 3

HCID 241BenzeneHCID 260Hydrogen Bromide2×HCID 54445285HCID 54445285, compound

Product 1

HCID 20322125HCID 20322125, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

30 g of (5-bromo-3-methylpentyl)-malonic acid diethyl ester were heated to the boil, while stirring, with 15 ml of 48% HBr and 15 ml of HBr/glacial acetic acid, whereby the low-boiling products were distilled off. After 7 hours the cooled reaction solution was distributed between benzene and water and the organic phase was evaporated with MgSO4 after drying and distilled off.

Workup

  1. distillationwere distilled off
  2. customAfter 7 hours the cooled reaction solution
  3. customthe organic phase was evaporated with MgSO4
  4. customafter drying
  5. distillationdistilled off

Sources & evidence

ORD record
ord-95047d2fe18649f4959650fe2b055a26
Source dataset
uspto-grants-1976_10
Patent number
US03984459

Reaction notes

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