反应详情

Following a procedure similar to that described in Example 1 but using 3.39 g. sodium in 200 ml. dry acetone, 20 g. valeramidine hydrochloride and 21.9 g. 4-methoxyphenyl isocyanate in 100 ml. dry acetone, there ws obtained after recrystallization from ethyl alcohol 15.5 g. of the hydrochloride of 1-(4-methoxyphenyl)-3-(pentanimidoyl)urea; m.p. 143.5°-145°C.

1. customafter recrystallization from ethyl alcohol 15.5 g