Acetone → HCID 152745637, compound

HRID 1287385Notes

Reaction equation

HRID 1287385 reaction equation
[Na].CC(C)=O.Cl.[C:7]([NH2:13])(=[NH:12])[CH2:8][CH2:9][CH2:10][CH3:11].[N+:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[N:23]=[C:24]=[O:25])([O-:16])=[O:15]>C1C=CC=CC=1>[N+:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[NH:23][C:24]([NH:12][C:7](=[NH:13])[CH2:8][CH2:9][CH2:10][CH3:11])=[O:25])([O-:16])=[O:15]

Participants

6

Reactant 4

HCID 180AcetoneHCID 768342-Nitrophenyl isocyanateHCID 5360545SodiumHCID 11615174Pentanimidamide Hydrochloride

Product 1

HCID 152745637HCID 152745637, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Following a procedure similar to that described in Example 1 but using 2.3 g. sodium in 150 ml. dry acetone, 13.6 g. valeramidine hydrochloride, and 16.4 g. 2-nitrophenyl isocyanate in 300 ml. benzene, there was obtained after recrystallization from ethyl alcohol 9.1 g. of the hydrochloride of 1-(2-nitrophenyl)-3-(pentanimidoyl)urea; m.p. 130°-132°C.

Workup

  1. customafter recrystallization from ethyl alcohol 9.1 g

Sources & evidence

ORD record
ord-772e40eea41c435f93e20a465818c1bc
Source dataset
uspto-grants-1976_10
Patent number
US03984467

Reaction notes

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