HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → HCID 178444014, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | 1-Chloro-2-isothiocyanatobenzene | HCID 123171 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | Heptanimidamide hydrochloride | HCID 14144282 | — |
| Solvent | Benzene hexane | HCID 110624 | — |
| Product | HCID 178444014 | HCID 178444014 | — |
Reaction Steps
Following a procedure similar to that described in Example 42 but using 3.4 g. sodium in 300 ml. acetone, 24.7 g. heptanamidine hydrochloride, and 25.9 g. 2-chlorophenyl isothiocyanate (b.p. 70°-74°C./0.5-1.0 mm.; prepared from 2-chloroaniline) in 125 ml. dry acetone there was obtained 1-(2-chlorophenyl)-3-(heptanimidoyl)-2-thiourea, m.p. 75°-77°C. (from benzene-n-hexane); hydrochloride (33.5 g.), m.p. 158°-160°C. (from acetonitrile).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03984467 |
| Source dataset | uspto-grants-1976_10 |
| ORD ID | ord-b4ccdd8ee39f420da929def58bdab3aa |
| Source note | uspto-grants-1976_10 |